Azathioprine and the enzyme NUDT15
Azathioprine is processed to a large extent by the enzyme NUDT15 and TPMT. The activity of this enzyme can vary considerably depending on your genetic predisposition, which means the efficacy of azathioprine can also differ from person to person.
Information about your genetic predisposition may therefore provide grounds for extra vigilance in relation to a treatment with azathioprine.
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